The powers of the Commission appear in Article V of the ICAOS. Among its primary powers, the Commission:

• Promulgates rules, which are binding on the states and have the force and effect of statutory law within each member state;
• Oversees, supervises, and coordinates the interstate movement of supervised individuals subject to the Compact;
• Enforces compliance with all the Compact rules and terms;
• Creating mechanisms for resolving disputes between states;
• Coordinates the Commission’s education, training, and awareness relative to supervised individual’s interstate movement;
• Establishes uniform standards for reporting, collecting, and exchanging data; and,
• Performs other functions as necessary to achieve the purposes of the Compact.